The Potential of Intranasal Light Therapy for Brain Stimulation


Available evidence supports intranasal light therapy for brain-related conditions such as mild cognitive impairment, Parkinson’s Disease, migraine, stroke. However, the present set of parameters have been based on optimizing the results for blood irradiation; which may be holding back its potential for better neurological outcomes.

We analysed the literature to arrive at reference parameters for optimum brain stimulation with low level light. MedicLights then developed intranasal light therapy devices based on these parameters, which we then used to develop case reports with a growing group of subjects for neurological outcomes, which include those already using legacy intranasal light therapy devices.

Studies lead us to select parameters that involve low level light in the near infrared red (NIR) range that pulses at 10 Hz to draw superior neural response. More specifically, the parameters could include a wavelength of 810 nm from a LED source, supported by a power density of 10 mW/cm², over daily treatment session of 25 minutes, and a duty cycle of 50 percent.

The LED beam footprint spans the underside of the brain, including the mid-brain area. With these specifications, the energy is 7.5 J/cm² (net of duty cycle) per session. Users reported improved neurological outcomes, although the results are more mixed (but without negative effects) from those without prior medical conditions.

The findings suggest that intranasal light therapy is promising as a brain stimulation method, to be validated with more specific and rigorous clinical studies.

Full paper: The Potential of Intranasal Light Therapy for Brain Stimulation