High Cholesterol and Intranasal Light Therapy


Several studies support the use of photobiomodulation (low level light therapy) to reduce low-density lipoprotein (LDL) cholesterol in blood.

Given that intranasal light therapy (or photobiomodulation) irradiates blood efficiently through the blood-rich nasal cavity, this facilitates the disaggregation of cholestrol in blood.

Research Examples

In one study, scientists randomly divided 30 patients with hyperlipidemia into two groups, 15 in a group treated with pharmaceutical drugs, and 15 in another group treated with low level laser intranasal light therapy for 45 minutes each time.

This was done daily for 7 consecutive days and then after a 5 day rest, for another 7 days. They found that intranasal therapy induced a significant decrease in total cholesterol. However, the decrease was less than that induced by pharmaceuticals.[1]

In another study – a clinical study originally designed to investigate how dissolved fat affects body chemistry led researchers to discover that low level laser therapy disrupts cholesterol formation.

The study involved twenty volunteers between the ages of 18 and 65 years. 75% of study participants that demonstrated overall reduction in cholesterol serum levels had a reduction ranging from -1.0 to -31.0 mg/dL.

For those participants demonstrating an overall reduction in cholesterol serum levels, 93% experienced a reduction in low density lipoprotein (LDL) levels (commonly labelled as “bad cholesterol”), with 47 percent revealing a reduction in LDL levels without experiencing a reduction in HDL levels (or “good cholesterol”).

Of the 20 participants, 60% also experienced a reduction in triglyceride levels. Summarily, 75 % of study participants had an overall reduction in cholesterol sum of 16.1 points. [2]

High cholesterol and red blood cell aggregation

The circulatory system of a person with high cholesterol will exhibit red blood cell (RBC) aggregation and increased blood viscosity. The increase in RBC aggregation is due to the high concentration of lipoproteins such as low density lipoproteins (LDL).[3]

Hence, photobiomodulation results in disaggregate RBC, thus reducing the level of unhealthy LDL.

Photobiomodulation disaggregates RBC

Low level laser therapy irradiation of blood within the red spectrum results in the disaggregation of RBC through a process known as photobiomodulation.

The figure below demonstrates the before and after effects of photobiomodulation in the red spectrum.


Figure 1: Blood samples before and after low level light therapy treatments


Photobiomodulation reduces LDL levels

This is also demonstrated by a study that covered 218 patients with diabetes both of type 1 and type 2, over 7 years, where high cholesterol and triglyceride readings were common among them.

They were all treated with low level light therapy (photobiomodulation) involving the irradiation of the blood through the intravenous method. As demonstrated in Figure 2 below.

Intravenous light irradiation method

Figure 2: Intravenous light irradiation method


In the study mentioned above, right from the beginning of the treatment – symptoms of peripheral blood circulation and neural conditions improved. The readings for total cholesterol, LDL cholesterol and tricglyceride levels became normal or improved with the simultaneous improvement in HDL levels.[5]

Furthermore, it was found that diabetes related diseases such as angiopathy (disease of the blood vessels and lymph ducts) also improved. No pharmaceuticals were given during the treatment period.

The authors also state that ILBI results in a stable hypolipidemic situation which prevents atherogenesis in patients with metabolic disorders, particularly in patients with renal pathologies.[6]

Separate tests also found that high cholesterol conditions in patients with coronary heart disease (CHD) also improved with low level laser treatment.[7]

After receiving a course of low-intensity infrared laser radiation treatment the patients displayed positive changes in blood lipid spectrum, which was associated with improvement in microcirculation, decrease in afterload, increase in economization of heart functioning and activity tolerance.

The obtained results demonstrate that the hypolipidemic effect of laser radiation is a substantial factor in the regression of coronary heart disease manifestations.

A newer light therapy method

The light therapy method used in the above studies was invasive and requires a trained technician to implement. This was before a newer method that operates under the same theory and achieve similar results by illuminating the nasal cavity, Intranasal Light Therapy as shown in Figure 3 below.


Figure 3: Intranasal light therapy

It is established that the intranasal method such as ours achieves similar outcomes as the intravenous blood irradiation method. View the evidence comparing intranasal with intravenous methods of irradiation.



1. Chi J, Hu G, Lin X, Qiu X, Liang D, Liu J, Chen J, Liu X, Hou L, Wang Y, Li Z, Liu S (2005). Study of the Therapy Effects of Low intensity Laser Rhinal Radiation on Dyslipidemia.  Acta Laser Biology Sinica. 14(4): 265-268 (in Chinese).

2 Announced and posted online by Laser Focus World on Apr 2009 – http://www.laserfocusworld.com/articles/2009/04/pilot-study-shows-low-level-laser-light-can-reduce-cholesterol-triglycerides.html.

3. R Scherer, A Morarescu, G Ruhenstroth-Bauer. The significance of plasma lipoproteins on erythrocyte aggregation and sedimentation. Br J Haemotol 1976 Feb;32(2):235-41

4. T.V. Kovalyova, A.V. Farvayeva, L.T. Pimenov, S.M. Denisov. Dynamics of hyperlipidemia and peripheral blood flow in patients with diabetes mellitus after the course of combined laser therapy in ambulatory polyclinic conditions. Laser Flashes Nov-Dec 2002.

5. Kovalyova TV, et al. Dynamics of lipid metabolism and peripheral blood flow rates in patients with atherosclerosis in conjunction with renal dysfunction after the course of combined laser therapy. Selected abstract from Laser & Health, Dec. 8-10, 1999, Moscow.

6. A P Vasilev, M A Sekisova, N N Streltsova, I N Senatorov. Laser correction of microcirculation disorders in patients having CHD with hypercholesterolemia. Klin Med (Mosk); 83(2):pp 33-7.